Mapping circuits, modeling motivation, guiding precision interventions, digital phenotyping and biofeedback
The NeuroSCOPE lab investigates the brain circuits underlying motivation and mood, with a particular focus on characterising depression. We are interested in combining multi-modal neuroscientific tools to not only deepen our understanding of the human brain but also to advance personalised mental healthcare. Using high-resolution 7T MRI, reinforcement learning paradigms, and digital phenotyping via EMAware technology, we aim to characterise motivation and its neural mechanisms. Through integrating neuroimaging with precision biofeedback interventions, we aim to map and modulate brain activity, implementing a rigorous and individualised approach to understanding and treating mood disorders.
Latest publications
Altered blood-based biomarkers in carpal tunnel syndrome. A systematic review and meta-analysis
Journal article
Menéndez-Cámara J. et al, (2026), Musculoskeletal Science and Practice, 84, 103561 - 103561
The alpha rhythm: from physiology to behavior.
Journal article
Jensen O. and Bonnefond M., (2026), Physiol Rev, 106, 1123 - 1159
Combined caLculation of Ultra-high field Biases (CLUB) With Sandwich: Fast, Simultaneous Estimation of 3D B0 and Multi-Channel B1 + Maps at 7 T.
Journal article
Pato Montemayor N. et al, (2026), Magn Reson Med, 95, 3341 - 3350
Key Readings
Digital measures of activity and motivation impact depression and anxiety in the real world
Cross-species dissection of the modular role of the ventral tegmental area in depressive disorders
Ventral tegmental area integrity measured with high-resolution 7-Tesla MRI relates to motivation across depression and anxiety diagnoses